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Angioplasty linked to higher death risk in diabetics

By Michelle Rizzo

NEW YORK (Reuters Health) - Diabetic patients who undergo angioplasty, a minimally invasive method of opening blocked heart vessels, are more likely to die in the years following treatment than their peers without diabetes, new research shows.

"Diabetic patients are known to have reduced survival following...angioplasty compared with nondiabetic patients," Dr. David L. Brown and colleagues from Beth Israel Medical Center, New York, write. "However, it is unknown whether this survival disadvantage has persisted" into the current era in which new drugs and devices are available that make angioplasty more effective and safe.

In the medical journal Diabetes Care, the researchers compared survival between diabetic and nondiabetic patients who underwent angioplasty for heart disease. More than 4000 patients were included in the study.

During 3 years of follow-up, 13 percent of diabetic patients died compared with just 8 percent of nondiabetic patients. After accounting for other related factors, the authors calculate that diabetics were 46 percent more likely to die than were nondiabetics.

Diabetics may fare worse because they have more severe blood vessel plaques than nondiabetics, Brown said in an interview with Reuters Health.

"These findings suggest that angioplasty...may not be the best form of treatment for diabetics," he said. "Diabetics may require more intensive medical therapy or even bypass surgery to achieve the best long-term outcomes."

SOURCE: Diabetes Care, May 2004.

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